Metabolic Psychiatry
Where psychiatry meets metabolism.
GLP-1/GIP medications and peptide therapy, prescribed and managed by a psychiatrist.
Mind. Body. Metabolism.
Mental health and metabolic health share the same wiring: inflammation, insulin signaling, reward circuits, and the gut-brain microbiom axis. Treating one without the other doesn't make sense anymore. My pracitce is on the cutting edge of these new breakthrough medications and treatments.
- Mood
- Anxiety
- Addiction
- Cognition
- Weight
- Insulin
- Energy
- Inflammation
What This Helps With
Anxiety & Stress
Selank and other neuroactive peptides offer mechanisms distinct from benzodiazepines and SSRIs, with growing evidence in generalized anxiety.
Cognition & Focus
Semax targets BDNF and neuroplasticity. Useful as a complement for clients focused on cognitive support and recovery.
Weight Gain from Psych Meds
Antipsychotics, mood stabilizers, and certain antidepressants can drive weight gain, insulin resistance, and metabolic syndrome. Managed by the same clinician who manages your psychiatric care.
Mood & Depression
Inflammation and insulin resistance are increasingly recognized as drivers of treatment-resistant depression. Metabolic-targeted strategies can complement standard care.
Gut-Brain Axis
For clients with overlapping GI and psychiatric symptoms, peptides like BPC-157 and KPV target gut-side inflammation that often shows up in mood.
Alcohol & Substance Use
GLP-1 medications modulate the same reward pathways involved in alcohol, nicotine, and food cravings. Strong clinical signal across multiple substances.
GLP-1 Medications
- Semaglutide (Ozempic / Wegovy)
- Tirzepatide (Mounjaro / Zepbound)
- Retatrutide (triple agonist, post-approval)
For weight, appetite, alcohol cravings, and the metabolic side effects of psychiatric medications.
Peptide Therapy
- Selank for anxiety
- Semax cognition, neuroplasticity
- BPC-157 gut-brain, recovery
- KPV anti-inflammatory
Compounded under physician prescription. Reviewed case-by-case alongside your psychiatric treatment.
Novel Psychiatric Medications
- Auvelity rapid-acting treatment for depression
- Vilazodone next generation anxiety medication
- Spravato intranasal esketamine
- Cobenfy first muscarinic antipsychotic
- Trintellix cognitive-supportive
A current-generation psychopharmacology toolkit, not just the medications that seem like spaghetti on the wall.
Lab & Diagnostic Testing
- Pharmacogenomics Genomind
- Inflammation Panel hs-CRP, IL-6, TNF-α
- Microbiome Analysis GI-MAP, stool sequencing
- Methylation MTHFR, folate pathway
- Metabolic Panel insulin, A1c, lipids
Testing that helps us pick medications more precisely and identify the metabolic and inflammatory drivers behind your symptoms.
Not every patient is a candidate. Clinical decisions are made after a full evaluation that weighs your medications, history, and goals.
Why a psychiatrist for this.
An obesity-medicine doctor can prescribe a GLP-1. A functional-medicine clinic can write for a peptide. What almost nobody offers in Manhattan is a board-certified psychiatrist who handles both — alongside your antidepressant, your mood stabilizer, your stimulant, your sleep med — as one integrated plan.
The same clinician thinking about your mind and the metabolism around it.
Frequently Asked Questions
Reviewed by Vijal Parikh, D.O., Board-Certified Psychiatrist Last reviewed May 2026
What is metabolic psychiatry?
Metabolic psychiatry treats mental health conditions by also addressing the metabolic systems that drive them, including insulin signaling, inflammation, the gut-brain axis, and reward circuitry. In practice, that means using GLP-1 medications, peptide therapy, targeted lab work, and conventional psychiatric medications as one integrated plan rather than parallel silos.
Can a psychiatrist prescribe GLP-1 medications like Ozempic, Wegovy, or Mounjaro?
Yes. Any licensed physician, including a board-certified psychiatrist, can prescribe semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and newer agents like retatrutide when clinically appropriate. The advantage of having a psychiatrist prescribe is that GLP-1 medications also influence mood, cravings, addictive behavior, and cognition, all of which sit squarely inside psychiatric care.
How is this different from a weight-loss clinic or med spa?
A weight-loss clinic typically focuses on the scale. This practice treats GLP-1s and peptides as psychiatric and neurometabolic tools used for binge eating, alcohol cravings, anxiety, ADHD-related dysregulation, and weight gain caused by antidepressants, mood stabilizers, or antipsychotics. The same clinician manages both your psych meds and your metabolic plan, so they're never working against each other.
Will GLP-1 or peptide therapy interact with my current psychiatric medications?
Most psychiatric medications can be safely continued alongside GLP-1 therapy and well-studied peptides, but specific interactions and dose adjustments need a careful review. That review is the first thing covered in the initial visit (current meds, recent labs, history, and goals) before anything is added or changed. See the main practice page for the broader range of psychiatric care offered alongside metabolic work.
Do you prescribe peptides like Selank, Semax, or BPC-157?
Yes, when clinically appropriate. Selank and Semax are used for anxiety and cognition; BPC-157 is used for inflammation and gut-related symptoms tied to mood. Peptides are sourced from licensed compounding pharmacies, dosed conservatively, and monitored with follow-up labs.
Is GLP-1 therapy covered by insurance?
Coverage for GLP-1 medications depends on your plan, your diagnosis, and the specific drug. Many commercial plans cover semaglutide or tirzepatide for type 2 diabetes or qualifying obesity criteria; coverage for off-label psychiatric use is less common. The visit itself is out-of-network, with superbills provided for reimbursement.
What lab work do you order?
Standard panels typically include fasting insulin, HbA1c, lipid panel, hs-CRP, comprehensive metabolic panel, thyroid function, vitamin D, B12, ferritin, and sex hormones when relevant. Labs are repeated at intervals to track response and adjust the plan.
I gained weight on an antidepressant or mood stabilizer. Can you help?
Yes. This is one of the most common reasons people come to the practice. Options range from switching to a more weight-neutral psychiatric medication, adding a GLP-1 agent, or both. The plan is built around staying psychiatrically stable while reversing the metabolic side effect. The main practice handles the underlying psychiatric care for ADHD, anxiety, and depression that often sits alongside this conversation.
Do you offer virtual visits for metabolic psychiatry?
Yes, for established patients within New York State. Initial evaluations are typically in-person at the Union Square office (201 E 16th St) so the first assessment, vitals, and exam are done together.
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